Dr. McCurdy CNN interview

UF Pharmacy faculty featured in CNN report on kratom and the opioid crisis

Christopher McCurdy, Ph.D., a professor of medicinal chemistry, was featured in a CNN.com report on kratom, an herb, and its potential to treat pain and opioid withdrawal.

Research Showcase, Med Chem Winners-1

Winners from 30th Annual Research Showcase

A record 89 poster entries and a keynote address about how technology is transforming clinical drug development highlighted the College of Pharmacy’s 30th Annual Research Showcase event on Feb. 17, […]

Nick Paciaroni, student, wins the oral presentation at the 2017 Drug Discovery Symposium

UF Drug Discovery Symposium Award Winners

Congratulations to the students and postdocs who participated in the oral and poster presentations as part of the 2017 Drug Discovery Symposium.

Key drug discovery experts from across Florida converge at 2017 UF Drug Discovery Symposium

The symposium featured nearly 130 participants and plenary speakers from the Dana-Farber Cancer Institute, Scripps Research Institute-Florida and National Cancer Institute.

Common, edible mushroom has potential to kill one type of leukemia cell, UF Health researchers find

Dr. Yousong Ding in the UF College of Pharmacy found the Coprinus comatus mushroom, commonly known as the lawyer’s wig or shaggy mane, killed human T-cell leukemia cells during laboratory tests.

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Welcome to the Department of Medicinal Chemistry

The Department of Medicinal Chemistry is located in the University of Florida College of Pharmacy and is an integral part of UF Health. The strategic location within the Health Science Center facilitates interdisciplinary collaborations and close interactions with clinicians, which catalyzes the translation from bench to bedside.

Our faculty teach in both Pharm.D. and the departmental Ph.D. program. Several faculty are also teaching in our online MS Pharmacy program. Our graduate students get exposed to the entire life cycle of a drug by participating in college-wide activities and receive outstanding in-depth training in early-stage drug discovery and modern medicinal chemistry.

The department has excellent facilities dedicated to major areas of medicinal chemistry research, and our faculty have been highly successful in attracting extramural research support. UF’s Preeminence initiative in drug discovery and development has supported an expansion of the department in focus research areas such as natural products and structure-based drug design and invested in major therapeutic areas, including cancer, anti-infectives, drug abuse and pain research.

Our impressive natural products inspired program encompasses the entire spectrum of multidisciplinary research from genomes to drugs, including genome mining, biosynthetic engineering, chemical synthesis and biological profiling of natural products and natural product-like compounds, leading to the corresponding in vitro and in vivo pharmacology, mechanistic studies, and preclinical evaluation of drug candidates. Several such lead compounds have been licensed by pharmaceutical companies.

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With many more small-molecule lead compounds emerging from our medicinal chemistry campaigns, utilizing target-based, phenotypic or virtual screens as well as genome scanning as starting points, our research platform provides exciting opportunities to both our current and future graduate students.

Hendrik Luesch, Ph.D.

Debbie and Sylvia DeSantis Chair in Natural Products Drug Discovery and Development |  Professor and Chair of the Department of Medicinal Chemistry

Faculty Search

The Department of Medicinal Chemistry in the College of Pharmacy at the University of Florida invites applications for a tenure-track faculty position at the assistant or associate professor level. Candidates should have a record of a strong independent research program in drug discovery and development or demonstrate outstanding potential to build such a program. Faculty hires will also participate in professional and graduate instructional efforts of the college. Area of specialization within medicinal chemistry is open, but should complement the interests of the department and the Center for Natural Products, Drug Discovery and Development and agree with institutional strategies adopted by the University of Florida to foster interdisciplinary research in cancer, infectious diseases, neuroscience and diabetes.

Fast Facts: UF Medicinal Chemistry

Meet Marci Smeltz, Ph.D. | Spring 2017 Graduate

Seminar Series and Guest Speakers

Dr. Ley lecture announcement

Guest Speaker: Dr. Thomas Leyh, 11/15

Controlling Human Sulfuryl-Transfer Biology" Wednesday, November 15th at 3pm Communicore Building, C1-15

Seminar Announcement, David Sherman

College-Wide Seminar, David Sherman, Ph.D.

The UF College of Pharmacy Department of Medicinal Chemistry welcomes David Sherman, Ph.D.,who will present on November 28th.

PHA 6934, Fall 2017 Seminar Series listing

Seminar in Medicinal Chemistry

Take a look at the scheduled seminar speakers and topics for the Fall ’17 semester.