Yi Zhang

Yi Zhang

Yi Zhang

Education

  • Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, PRC, Sept. 2011 – June 2013                                  
  • Master of Medicinal Chemistry, School of Pharmacy China Pharmaceutical University, Nanjing, Jiangsu, PRC, Sept. 2010 – June 2013
  • B.S., Pharmaceutical Engineering, China Pharmaceutical University, Nanjing, Jiangsu, PRC,  Sept. 2006 – June 2010

Entry Date into the Medicinal Chemistry PhD program:  Fall 2013
 Curriculum Vitae

Research Interests

  • Biosynthesis of natural products
  • Synthetic biology
  • Medicinal chemistry

Publications

Yi Zhang, Kunhua Li, Guang Yang, Joshua L McBride, Steven D Bruner, Yousong Ding, A Distributive ATP Grasp Ligase Macrolactonizes Multiple Microviridin Core Peptides within a Single Substrate, publication in progress.

Guangde Jiang, Peilan Zhang, Guang Yang, Yi Zhang, Lanlan Tang, Ran Zuo, Magan Powell, Max Teplitski, Valerie Paul, Hendrik Luesch, Rui Xiao, and Yousong Ding, Interconversion of Fungal Epithiodiketopiperazines with Α, Β-Polysulfide Bridges, publication in progress.

Guang Yang, Yi Zhang, Nicholas Lee, Monica Cozad, Sara Kearney, Hendrik Luesch, and Yousong Ding, Cyanobacterial Sfp-type Phosphopantetheinyl Transferases Functionalize Carrier Proteins of Diverse Biosynthetic Pathways, Scientific Reports, doi:10.1038/s41598-017-12244-3.

Ran Zuo, Yi Zhang, Chao Jiang, John C. Hackett, Rosemary Loria, Steven D. Bruner, and Yousong Ding, Engineered P450 biocatalysts show improved activity and regio-promiscuity in aromatic nitration, Scientific Reports, doi:10.1038/s41598-017-00897-z.

Yi Zhang, Rosemary Loria, and Yousong Ding, Applications of Natural Products from Soil Microbes, Soil ecosystems services.2015.0023.

Ran Zuo, Yi Zhang, Jose C. Huguet-Tapia, Mishal Mehta, Evelina Dedic, Steven D. Bruner, Rosemary Loria, and Yousong Ding, An Artificial Self-Sufficient Cytochrome P450 Directly Nitrates Fluorinated Tryptophan Analogs with a Different Regio-Selectivity, Biotechnology Journal, 2016, 11, 624-32.

Lu, Jia, Vivian Wong, Yi Zhang, Trung Tran, Liang Zhao, Amy Xia, Tianbing Xia and Xin Qi. Distinct Conformational Transition Patterns of Noncoding 7sk snRNA and HIV Tar RNAs Upon Tat Binding, Biochemistry 2014, 53(4): 675-681.

Yi Zhang, Jiang Wang, Yong Nian, Hongbin Sun and Hong Liu, Palladium-Catalyzed Regioselective 2-Carbethoxyethylation of 1H– Indoles By C-H Activation: One-Step Synthesis of Ethyl 2-(1H-Indol-2-Yl) Acetates, Organic Chemistry: Current Research, 2014, 3:124.

Yi Zhang Hongbin Sun. A practical synthesis of 3-pyridineboronic acids, CN 201310193521.9;

Hong Liu, Xin Xie, Diliang Guo, Jing Li, Yi Zhang et al. Novel tetrahydroisoquinline compounds for benign prostatic hyperplasia, CN 201210347340.2.

Contact Information

Email: yzhang2013@ufl.edu