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UF Health University of Florida
Department of Medicinal Chemistry College of Pharmacy
People Overview

Aaron Garrison

Aaron Garrison
Aaron Garrison

Education

  • Ph.D., Pharmaceutical Sciences – Medicinal Chemistry, University of Florida, 2013 – 2017
  • B.A., Chemistry, Biochemistry Emphasis, University of South Florida, 2009 – 2013

Entry date into medicinal chemistry Ph.D. program: 2013

Curriculum Vitae

Research Interests

  • Medicinal Chemistry
  • Organic Synthesis
  • Antimicrobial Agents

Publications

  1. Yousaf, H. H.; Garrison, A. T.; Abouelhassan, Y.; Basak, A.; Jones, J. B.; Huigens III, R. W. “Identification of Nitroxoline and Halogenated Quinoline Analogues with Antibacterial Activities against Plant Pathogens.” ChemistrySelect, 2017, 2, 6235-6239.
  2. Garrison, A. T.; Huigens III, R. W. “Eradication of Bacterial Biofilms with Natural Products and Their Inspired Analogues that Operate Through Unique Mechanisms.” Curr. Top. Med. Chem., 2017, 17, 1954-1964.
  3. Invited Review for Thematic Issue: “Recent Advances in Anti-biofilm Strategies”
  4. Garrison, A. T.; Abouelhassan, Y.; Yang, H.; Yousaf, H. H.; Nguyen, T.; Huigens III, R. W. “Microwave-Enhanced Friedländer Synthesis for the Rapid Assembly of Halogenated Quinolines with Antibacterial and Biofilm Eradication Activities against Drug Resistant and Tolerant Bacteria.” Med. Chem. Commun., 2017, 8, 720-724.
  5. 2016 MedChemComm Hot Article; Invited for Themed Issue: “New Talent: Americas”
  6. Zuo R.; Garrison A. T.; Basak A.; Zhang P.; Huigens III, R. W.; Ding Y. “In vitro antifungal and antibiofilm activities of halogenated quinoline analogues against Candida albicans and Cryptococcus neoformans.” Int. J. Antimicrob. Agents, 2016, 48, 208-211.
  7. Garrison, A. T.; Abouelhassan, Y.; Norwood IV, V. M.; Kallifidas, D.; Bai, F.; Nguyen, M.; Rolfe, M. Burch, G. M., Jin, S., Luesch, H.; Huigens III, R. W. “Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines that Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis.” J. Med. Chem., 2016, 59, 3808-3825.
  8. Garrison, A. T.; Abouelhassan, Y.; Kallifidas, D.; Bai, F.; Ukhanova, M.; Mai, V.; Jin, S.; Luesch, H.; Huigens III, R. W. “Halogenated Phenazines that Potently Eradicate Biofilms, MRSA Persister Cells in Non-Biofilm Cultures and Mycobacterium tuberculosis.” Angew. Chem. Int. Ed., 2015, 54, 14819-14823.
  9. Abouelhassan, Y.; Garrison, A. T.; Bai, F.; Norwood IV, V. M.; Nguyen, M.; Jin, S.; Huigens III, R. W. “A Phytochemical-Halogenated Quinoline Combination Therapy Strategy for the Treatment of Pathogenic Bacteria.” ChemMedChem, 2015, 10, 1157-1162.
  10. Garrison, A. T.; Bai, F.; Abouelhassan, Y.; Paciaroni, N. G.; Jin, S.; Huigens III, R.W. “Bromophenazine Derivatives with Potent Inhibition, Dispersion and Eradication Activities against Staphylococcus aureus Biofilms.” RSC Adv., 2015, 5, 1120-1124.
  11. Abouelhassan, Y.; Garrison, A. T.; Burch, G. M.; Wong, W.; Norwood IV, V. M.; Huigens III, R. W. “Discovery of quinoline small molecules with potent dispersal activities against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a scaffold hopping strategy.” Bioorg. Med. Chem. Lett., 2014, 24, 5076-5080.

Contact Information

Email: atgarrison@ufl.edu