Education
- Ph.D. student, Medicinal Chemistry and Pharmacognosy, Ohio State University, Sept. 2014 – July 2016
- M. S., Medicinal Chemistry, China Pharmaceutical University, Sept. 2008 – July 2011
- B. S.,Pharmacy, China Pharmaceutical University, Sept. 2004 – July 2008
Entry Date into the Medicinal Chemistry PhD program: Fall 2016
Research Interests
- Design, synthesis and assay of small molecules
- Preparation and characterization for rare earth inorganic nano-materials
Publications
X.Z. Yang, W.H. Yang, Y.G. Xu, X.J. Diao, G.W. He, G.Q. Gong, Synthesis and antithrombotic evaluation of novel dabigatran prodrugs containing a cleavable moiety with anti-platelet activity [J], European Journal of Medicinal Chemistry, 57 (2012) 21-28.
X.Z. Yang, X.J. Diao, W.H. Yang, F. Li, G.W. He, G.Q. Gong, Y.G. Xu, Design, synthesis and antithrombotic evaluation of novel dabigatran prodrugs containing methyl ferulate [J], Bioorganic & Medicinal Chemistry Letters, 23 (2013) 2089-2092.
Y.Z. Li, G.Q. Gong, W.H. Yang, X.H. Wang, M.L. Jiang, Y. Zhou, X.Z. Yang, Y.G. Xu, G.W. HeAntithrombotic activity of HY023016, a novel Dabigatran prodrug evaluated in animal thrombosis models [J], Thrombosis Research 131 (2013) 425-435.
Yungen Xu, Xiaozhi Yang, Guoqing Gong, Wenhui Yang, Guangwei He, Feng Li, The preparation and medical application of a series of oral thrombin inhibitors [P], CN102838588(A), 2012-12-26.
Yungen Xu, Xiaozhi Yang, Guangwei He, Guoqing Gong, Wenhui Yang, Xiaojuan Diao, Shaoxing Chu, The preparation and antithrombotic application of dabigatran derivatives [P], CN102875533(A), 2013-01-16.
X.Z. Yang, X.J. Diao, G.Q. Gong, Y.G. Xu, Design and Synthesis of Novel Derivatives of Dabigatran Based-on Scaffold Hopping [A], National Medicinal Chemistry Conference – the source of the drug innovation abstract collection [C], (2011) 81.
Yungen Xu, Xiaozhi Yang, Guoqing Gong, Wenhui Yang, Guangwei He, Xiaojuan DiaoNon-peptide thrombin inhibitors as well as preparation method and medical application thereof [P], CN102250099 (A), 2011-11-23.
N. Jin, Y. Yang, W. Xu, X.Z. Yang, G. Gong, Y. Xu, Synthesis and Bioactivity of Substituted Benzoylguanidine Derivatives as Potent Na+/H+ Exchanger Inhibitors [J], Chinese Journal of Chemistry, 30 (2012) 333-340.
Guoqing Gong, Xiangmin Jiang, Linlin Li, Shujuan Ren, Yungen Xu, Chao Xu, Xiaozhi Yang, Yajun Yun, Guomin Zhang, Benzoylguanidine-trimetazidine conjugate, as well as preparation method and medical application thereof [P], CN101747292 (A), 2010-06-23.
Y. Zhang, A. Zheng, X.Z. Yang, H. He, Y. Fan, C. Yao, Cubic GdFeO3 Particle by a Simple Hydrothermal Synthesis Route and Its Photoluminescence and Magnetic Properties [J], CrystEngComm, 14 (2012) 8432-8439.
Contact Information
Email: xiaozhi.yang@ufl.edu