Laura E Hanold

Laura E Hanold,

Biological Scientist III

Department: Medicinal Chemistry
Business Phone: (352) 273-7866
Business Email: hanoldl@ufl.edu

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0003-4492-9885

Publications

2023
Carbohydrate-Small Molecule Hybrids as Lead Compounds Targeting IL-6 Signaling
Molecules. 28(2) [DOI] 10.3390/molecules28020677. [PMID] 36677735.
2018
Conformationally constrained peptides target the allosteric kinase dimer interface and inhibit EGFR activation.
Bioorganic & medicinal chemistry. 26(6):1167-1173 [DOI] 10.1016/j.bmc.2017.08.051. [PMID] 28911855.
2017
Macrocyclic peptides decrease c-Myc protein levels and reduce prostate cancer cell growth.
Cancer biology & therapy. 18(8):571-583 [DOI] 10.1080/15384047.2017.1345384. [PMID] 28692379.
2017
Targeting kinase signaling pathways with constrained peptide scaffolds.
Pharmacology & therapeutics. 173:159-170 [DOI] 10.1016/j.pharmthera.2017.02.014. [PMID] 28185915.
2016
Correction: Hydrophobic Core Variations Provide a Structural Framework for Tyrosine Kinase Evolution and Functional Specialization.
PLoS genetics. 12(8) [DOI] 10.1371/journal.pgen.1006265. [PMID] 27513745.
2016
Hydrophobic Core Variations Provide a Structural Framework for Tyrosine Kinase Evolution and Functional Specialization.
PLoS genetics. 12(2) [DOI] 10.1371/journal.pgen.1005885. [PMID] 26925779.
2016
Targeting the WASF3-CYFIP1 Complex Using Stapled Peptides Suppresses Cancer Cell Invasion.
Cancer research. 76(4):965-73 [DOI] 10.1158/0008-5472.CAN-15-1680. [PMID] 26676744.
2015
Design of a selenylsulfide-bridged EGFR dimerization arm mimic.
Bioorganic & medicinal chemistry. 23(12):2761-6 [DOI] 10.1016/j.bmc.2015.03.040. [PMID] 25840798.
2015
Inhibiting EGFR dimerization using triazolyl-bridged dimerization arm mimics.
PloS one. 10(3) [DOI] 10.1371/journal.pone.0118796. [PMID] 25790232.
2015
Neurochondrin is an atypical RIIα-specific A-kinase anchoring protein.
Biochimica et biophysica acta. 1854(10 Pt B):1667-75 [DOI] 10.1016/j.bbapap.2015.04.018. [PMID] 25916936.
2015
PKA-type I selective constrained peptide disruptors of AKAP complexes.
ACS chemical biology. 10(6):1502-10 [DOI] 10.1021/acschembio.5b00009. [PMID] 25765284.

Grants

May 2022 ACTIVE
Targeting CIP2A for the Potential Treatment of Ovarian Cancer
Role: Co-Investigator
Funding: US ARMY MED RES ACQUISITION

Contact Details

Phones:
Business:
(352) 273-7866
Emails:
Business:
hanoldl@ufl.edu
Addresses:
Business Mailing:
PO Box 100485
GAINESVILLE FL 32610
Business Street:
1345 CENTER DR
GAINESVILLE FL 32610