The Department of Medicinal Chemistry has excellent facilities for research in these major areas of medicinal chemistry. Faculty have been highly successful in attracting extramural research support for the past several years.
Faculty and Research Areas
- Jane Aldrich – Peptide Chemistry and Drug Discovery and Development
- Lina Cui – Molecular Imaging and Anticancer Drug Discovery
- Yousong Ding – Biosynthetic Engineering
- Chenglong Li – Structure-based Computer-aided Drug Design and Discovery
- Yanjun Li – Artificial intelligence-driven drug discovery
- Xingui Liu – Discovery of proximity agents as potential therapies for cancer and other diseases
- Hendrik Luesch – Marine Natural Products Drug Discovery and Development
- Christopher R. McCurdy – Medicinal Chemistry and Drug Development
- Wenjun Xie – Enzyme engineering and covalent drug artificial intelligence
- Chengguo (Chris) Xing – Pharmacognosy Chemical Biology and Drug Discovery
- Guangrong Zheng – Synthesis and Medicinal Chemistry for Cancer and Age-Related Diseases
Department Equipment & Facilities
- HPLC systems (Shimadzu)
- ChemiDoc Imager MP Imaging (BioRad)
- AVANCE NEO 600 MHz NMR spectrometer with N2-Cryo-Platform for PRODIGY probe
- 3200 QTRAP triple quad/linear ion trap LC/MS/MS (Applied Biosystems)
- High resolution LC Q-Exactive orbitrap mass spectrometer (ThermoSci)
- Optima MAX-XP ultracentrifuges (Beckman Coulter)
- Scintillation counters (Beckman)
- Fluorescence/UV microplate readers (Biotek/PerkinElmer)
- Polarimeter (PerkinElmer)
- Anaerobic growth chamber (Whitley DG250 workstation)
- Autoclaving facilities
- Tissue culture lab facilities
State-of-the-art equipment are available in individual research faculty laboratories.
Additional training/computational and equipment facilities available through AMRIS and ICBR.
AVANCE NEO 600 MHz NMR spectrometer with N2-Cryo-Platform for PRODIGY probe
3200 QTRAP triple quad/linear ion trap LC/MS/MS
High resolution LC Q-Exactive orbitrap mass spectrometer